Ammonia → HCID 53770277, compound

Participants

Reaction Steps

Lithium metal, 1.2 g., in 1000 ml. of anhydrous ammonia and 4.03 g. (10 mmole) of 5,6,7,8,9,10-hexahydro-2-hydroxy-3-(1-methyl-4-phenylbutyl)-10-oxo-5,6,6-trimethylbenzo[c]quinoline in 500 ml. of tetrahydrofuran were reacted by the procedure of Example 9 and the resulting mixture of 6a,10a-cis and 6a,10a-trans isomers was isolated and separated by silica gel chromatography as described therein.

Provenance & Evidence