HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → Benzyl Benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | Tributylamine | HCID 7622 | — |
| Reactant | 2-Chloro-1-methylpyridin-1-ium 4-methylbenzene-1-sulfonate | HCID 10990220 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzyl Benzoate | HCID 2345 | 83% |
Reaction Steps
To a CH2Cl2 (2 ml) solution of 2-chloro-1-methylpyridinium p-toluenesulfonate (720 mg, 2.4 mmol) was added a mixture of benzyl alcohol (216 mg, 2.0 mmol), benzoic acid (244 mg, 2.0 mmol) and tri-n-butylamine (888 mg, 4.8 mmol) in CH2Cl2, and the resulting mixture was refluxed for 3 hours. After evaporation of the solvent, the residue was separated by silica gel column chromatography, and benzyl benzoate was isolated in 83% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04206310 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-667898514b364121a6c83c1751bfcfe8 |
| Source note | uspto-grants-1980_06 |