反应详情

A solution of 24.9 g of potassium permanganate and 18.7 g of magnesium sulfate in 498 ml of water was added dropwise during 1.5 hours to a solution of 22.23 g of 1-cyclohexenemethanol in 373 ml of ethanol. During the dropwise addition, the reaction mixture temperature was maintained at 15°-20°. The reaction mixture was filtered to remove the by-product manganese dioxide. The filtrate was evaporated under reduced pressure to a residual oil. The residual oil was taken up in ethanol and dried with magnesium sulfate. The mixture was filtered and the filtrate evaporated under reduced pressure to a residual oil. The residual oil was distilled using a short-path distilling system to give 6.44 g of 1,2-dihydroxycyclohexanemethanol; bp 124°-125°/0.025 mm.

1. additionDuring the dropwise addition
2. temperaturethe reaction mixture temperature was maintained at 15°-20°
3. filtrationThe reaction mixture was filtered
4. customto remove the by-product manganese dioxide
5. customThe filtrate was evaporated under reduced pressure to a residual oil
6. dry with materialdried with magnesium sulfate
7. filtrationThe mixture was filtered
8. customthe filtrate evaporated under reduced pressure to a residual oil
9. distillationThe residual oil was distilled