1,2-Diaminocyclohexane → HCID 22811247, compound

Participants

Reaction Steps

10.8 g β,β-dimethylacrylic acid was placed in a 250 ml flask, and 10 ml toluene was added followed by 11.4 g 1,2-diaminocyclohexane. The mixture is heated under an inert gas atmosphere, preferably argon, at 175°-180° C. with a Dean-Stark trap. 1.6 ml water was collected. The mixture is cooled down after 7 hr. Toluene was removed under vacuum. The reaction product obtained is recrystallized from acetone to give 2 g of a white crystalline product having a m.pt. of 188°-189° C.

Provenance & Evidence