Mci-186 → HCID 20335442, compound

Participants

Reaction Steps

The suspension of 3.0 g of 1-phenyl-3-methyl-2-pyrazolin-5-one in 60 ml benzene is treated with 2.0 g of triethylamine, warmed until dissolution and combined with 2.8 g of p-nitrophenylisocyanate in 30 ml of benzene while stirring. After standing for several hours at room temperature, it is filtered and the residue washed with benzene to yield the 1-phenyl-3-methyl-4-(p-nitrophenylcarbamoyl)-2-pyrazolin-5-one triethylammonium salt melting at 185°-192°.

Provenance & Evidence