HCID 15099417, compound → HCID 15099420, compound

Participants

Reaction Steps

In 100 ml of ethanol was dissolved 2 g of 1-(p-nitrobenzyl)-2-phenyl-4-chloroimidazole-5-acetic acid, and following addition of 300 mg of 10% palladium-on-carbon, the solution was shaken in hydrogen streams for 2 hours. The catalyst was filtered off and the filtrate was concentrated to dryness under reduced pressure and recrystallized from ethanol-hexane. By the above procedure was obtained 1.4 g of 1-(p-aminobenzyl)-2-phenyl-4-chloroimidazole-5-acetic acid as colorless needles, m.p. 141°-145° C. (decomp.)

Provenance & Evidence