反应详情

A solution of 20 g. (0.069 mole) of 4-nitro-N-(1,2-diethyl-4-pyrazolidinyl)benzamide in ethanol was treated with Raney nickel and shaken in three atmospheres of hydrogen in a Parr apparatus at room temperature for two hours. The mixtures was filtered, the filtrate concentrated and the residue crystallized from isopropyl ether-ethyl acetate. The product (12.0 g.; 66.5%) melted at 119°-121° C.

1. filtrationThe mixtures was filtered
2. concentrationthe filtrate concentrated
3. customthe residue crystallized from isopropyl ether-ethyl acetate