5-amino-3-methylquinolin-4(1H)-one → Diethyl[3-methoxy-4-({4-[(3-methyl-4-oxo-1,4-dihydroquinolin-5-yl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)benzyl]phosphonate
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:30][c:31]1[c:32]2[c:33](=[O:42])[c:34]([CH3:41])[cH:35][nH:36][c:37]2[cH:38][cH:39][cH:40]1>>[c:2]1([NH:30][c:31]2[c:32]3[c:33](=[O:42])[c:34]([CH3:41])[cH:35][nH:36][c:37]3[cH:38][cH:39][cH:40]2)[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ca057d14b2fc422bb8d11d5b2cb7ad96
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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