3,5-Dichlorobenzoyl chloride → HCID 23453046, compound

HRID 1706468Notes

Reaction equation

HRID 1706468 reaction equation
ClC1C=C(C=C(Cl)C=1)[C:5](Cl)=[O:6].Cl[C:13]1[CH:14]=[C:15]([CH:31]=[C:32]([Cl:34])[CH:33]=1)[C:16]([NH:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][C:26]([O:28]CC)=[O:27])=[CH:21][CH:20]=1)=[O:17].ClC1C=C(C=C(Cl)C=1)C(NC1C=CC(CC(O)=O)=CC=1)=O>>[Cl:34][C:32]1[CH:33]=[CH:13][C:14]([O:6][CH3:5])=[C:15]([CH:31]=1)[C:16]([NH:18][C:19]1[CH:20]=[CH:21][C:22]([CH2:25][C:26]([OH:28])=[O:27])=[CH:23][CH:24]=1)=[O:17]

Participants

4

Reactant 3

HCID 761913,5-Dichlorobenzoyl chlorideHCID 23453053HCID 23453053, compoundHCID 23453086HCID 23453086, compound

Product 1

HCID 23453046HCID 23453046, compound

Procedure

with 3,5-dichlorobenzoyl chloride, ethyl 4-(3,5-dichlorobenzamido)-phenylacetate; m.p. 152° C. (crude melting point); and from this, by saponification, 4-(3,5-dichlorobenzamido)-phenylacetic acid; m.p. 189° C., after recrystallization from ethanol-water.

Workup

  1. customm.p. 189° C., after recrystallization from ethanol-water

Sources & evidence

ORD record
ord-bc026fd6f2174ab2a8a0fa528b925597
Source dataset
uspto-grants-1980_06
Patent number
US04207341

Reaction notes

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