Ammonia → HCID 53917262, compound

HRID 1706501Notes

Reaction equation

HRID 1706501 reaction equation
[NH3:1].[C:2]1([CH:8](Br)[CH2:9][CH2:10][O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>>[C:2]1([CH:8]([NH2:1])[CH2:9][CH2:10][O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 20336053HCID 20336053, compound

Product 1

HCID 53917262HCID 53917262, compound

Procedure

1-Phenyl-3-phenoxypropylamine was prepared by the reaction of anhydrous ammonia and 1-phenyl-3-phenoxypropylbromide in a sealed vessel by the above procedure. The compound distilled at 137°-139° C. at 0.03 torr. The corresponding hydrochloride salt melted at 159°-161° C. after recrystallization from an ethyl acetate-acetone solvent mixture

Workup

  1. distillationThe compound distilled at 137°-139° C. at 0.03 torr
  2. customThe corresponding hydrochloride salt melted at 159°-161° C. after recrystallization from an ethyl acetate-acetone solvent mixture

Sources & evidence

ORD record
ord-073b1fd05e194603b6dda8750fa9205d
Source dataset
uspto-grants-1980_06
Patent number
US04207343

Reaction notes

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