Methanol → HCID 54343254, compound

HRID 1706557Notes

Reaction equation

HRID 1706557 reaction equation
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[CH2:15][C:16]([O:18]C)=[O:17].C(=O)([O-])[O-].[Na+].[Na+].CO>O>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[CH2:15][C:16]([OH:18])=[O:17]

Participants

5

Reactant 3

HCID 887MethanolHCID 10340Sodium CarbonateHCID 53970531HCID 53970531, compound

Product 1

HCID 54343254HCID 54343254, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 25 g. of methyl 1,6-dimethoxy-2-naphthylacetate, 15 g. of sodium carbonate, 200 ml. of methanol, and 25 ml. of water are allowed to stand for 24 hours. The reaction mixture is then acidified with 200 ml. of 2 N hydrochloric acid and extracted with methylene chloride. The extracts are combined, washed with water, dried over sodium sulfate, and evaporated to yield 1,6-dimethoxy-2-naphthylacetic acid.

Workup

  1. additionA mixture of 25 g
  2. extractionof 2 N hydrochloric acid and extracted with methylene chloride
  3. washwashed with water
  4. dry with materialdried over sodium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-1d9de166e01748119d127b0760b40363
Source dataset
uspto-grants-1980_06
Patent number
US04207241

Reaction notes

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