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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1706648Generated: October 25, 2026

Diethyl 2-diethylphosphono-2,4,4-trimethyladipate → 2,4,4-Trimethyl-2-phosphonoadipic acid

https://huagongshe.com/reaction/1706648

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl 2-diethylphosphono-2,4,4-trimethyladipateHCID 53764006—
SolventHydrogen BromideHCID 260—
Product2,4,4-Trimethyl-2-phosphonoadipic acidHCID 3017766—

Reaction Steps

Hydrolysis of this ester in concentrated hydrobromic acid gave 2,4,4-trimethyl-2-phosphonoadipic acid as a hygroscopic solid having a 31P chemical shift of -25 ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04208344
Source datasetuspto-grants-1980_06
ORD IDord-97846f463fb94d0fab0854c2e017a1b8
Source noteuspto-grants-1980_06