Ethanol → HCID 20334096, compound

Participants

Reaction Steps

The crude product obtained in step (a) is dissolved in anhydrous ethanol (150 ml) with thioacetamide (37.5 g; 0.5 mole). The mixture is stirred for 70 hours at room temperature, after which the ethanol is distilled off and the residue is taken up into water and ethyl ether. The ether phase is repeatedly extracted with 2 N sulfuric acid, and is then combined with the aqueous phase. The latter is adjusted to pH 7: the oil which separates is extracted with ether and distilled under reduced pressure: b.p.0.2 =135°-140° C.; Weight: 78.5 g. Overall yield: 54%.

Provenance & Evidence