Thiourea → HCID 53706046, compound

HRID 1706705Notes

Reaction equation

HRID 1706705 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[CH2:5][CH2:6]Cl.[NH2:12][C:13]([NH2:15])=[S:14]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[CH2:5][CH2:6][S:14][C:13](=[NH:12])[NH2:15]

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 23334398HCID 23334398, compound

Product 1

HCID 53706046HCID 53706046, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3,4-Dichlorophenethyl chloride (0.8 g., 0.004 mol.) and thiourea (0.26 g., 0.0035 mol.) in 25 ml. of ethanol were refluxed for two days. The mixture was concentrated and the residue treated with ether to give a solid which was recrystallized from acetone to yield carbamimidothioic acid 3,4-dichlorophenethyl ester, m.p. 135°-139° C.

Workup

  1. concentrationThe mixture was concentrated
  2. additionthe residue treated with ether
  3. customto give a solid which
  4. customwas recrystallized from acetone

Sources & evidence

ORD record
ord-fc8ae09fec0146c1900469ef21012189
Source dataset
uspto-grants-1980_06
Patent number
US04208430

Reaction notes

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