反应详情

A mixture of 0.26 g. of 3'-(2-methylphenyl)-spiro[isobenzofuran-1(3H),5'(4'H)-isoxazol]-3-one, 4ml. of water, 4 ml. of dioxane and 0.10 ml. of concentrated sulfuric acid was stirred at reflux for one hour, allowed to cool and diluted with 15 ml. of water. The resultant oil was stirred several minutes to give 0.24 g. of white solid; m.p. 162°-163.5° C. in 92% yield.

1. additionA mixture of 0.26 g
2. temperatureat reflux for one hour
3. temperatureto cool
4. additiondiluted with 15 ml
5. customto give 0.24 g