反应详情

Following the above procedure 10.0 g of the potassium salt of 3-(1-methylethyl)-1H-2,1,3-benzothiadiazin- -4 (3H)-one-2,2-dioxide was caused to react with 8.9 ml of lauroyl chloride at ca 25° C. After 48 hours, the mixture was filtered and the solvent removed from the filtrate in vacuo to afford 14.1 g of crude product. This was washed with two 50 ml-portions of methanol to afford upon air drying 3-(1-methylethyl)-1-(1-oxododecanyl)-1H-2,1,3-benzothiadiazin-4 (3H)-one-2,2-dioxide, m.p. 57.5°-58.5° C.

1. filtrationthe mixture was filtered
2. customthe solvent removed from the filtrate in vacuo