HRID1706832

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID175

Acetate

C2H3O2-

HCID702

Ethanol

C2H6O

HCID234533

n-carbamoyl-2-iodoacetamide

C3H5IN2O2

$结构：CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)/C(=N\O)c3ccco3)[C@H]2SC1.[Na+]$

HCID23694123

未命名化合物

PRODUCTS

生成物

$结构：CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\OCC(=O)NC(N)=O)c3ccco3)[C@H]2SC1$

HCID12769257

未命名化合物

收率 34%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

This compound was prepared from iodoacetylurea and (6R,7R)-3-acetoxymethyl-7-[Z-2-(fur-2-yl)-2-hydroxyiminoacetamido]-ceph-3-em-4-carboxylic acid sodium salt by the method described in Example 1. λmax (EtOH) 274 nm (ε 17,300), νmax (Nujol) 3420, 3260 (--NH--, --NH2), 3700-2100 (bonded OH), 1780 (β-lactam), 1720(--CO2H, acetate), 1700, 1570, 1545 cm-1 (CONH, CONH2), τ (DMSO d6) 2.11, 3.3, 3.18 (furyl), 5.28 (--O--CH2 --), 0.09 (--CONHCO--), 2.5 (CONH2), 0.11 (CONH), 4.1 (7 H), 4.78 (6 H), 6.29, 6.51 (2--CH2), 4.95, 5.28 (3 --CH2), 7.93 (CH3CO--). Yield: 34%.