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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1706846Generated: October 26, 2026

Acetic Anhydride → Vinblastine

https://huagongshe.com/reaction/1706846

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
Reactant4-DesacetylvinblastineHCID 197026—
ProductVinblastineHCID 13342—

Reaction Steps

0.29 g of deacetyl-vinblastine is dissolved in 3 ml of acetic anhydride and the solution is allowed to stand for one hour at room temperature. The thus obtained vinblastine is isolated from the reaction mixture in the usual way and then converted into the sulfate salt. 0.28 g of vinblastine sulfate is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04209443
Source datasetuspto-grants-1980_06
ORD IDord-45cf85c6278c47f8bbe682054793a7ef
Source noteuspto-grants-1980_06