Ethylene Glycol → HCID 86737061, compound

Participants

Reaction Steps

A mixture of 2 g of 9,9-ethylenedioxy-15-oxo-13-prostenoic acid ethyl ester, 100 ml of dry benzene, 10 ml of ethyleneglycol and 0.2 g of p-toluenesulphonic acid is boiled for 20 hours on a water separator. After cooling the mixture is diluted with 100 ml of diethyl ether and washed with aqueous NaHCO3 solution and water. The organic phase is dried over Na2SO4 and the solvent is distilled. After chromatographic purification of the residue (silica gel/diisopropyl ether), 9,9;15,15-bis-(ethylenedioxy)-13-prostenoic acid ethyl ester is obtained.

Provenance & Evidence