反应详情

A mixture of 10.0 g. of p-chloroacetophenone and 25 ml. of dimethylformamide dimethylacetal is refluxed for 3 hours. Evaporation gives a thick oil which crystallized with the addition of hexane, to give the product, m.p. 78.5°-80.5° C. Recrystallization from methylene chloride and hexane provides the product of the Example as crystals, m.p. 83°-84° C.

1. additionA mixture of 10.0 g
2. customEvaporation
3. customgives a thick oil which
4. customcrystallized with the addition of hexane
5. customto give the product, m.p. 78.5°-80.5° C
6. customRecrystallization from methylene chloride and hexane
7. customprovides the product of the Example as crystals, m.p. 83°-84° C.