HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Methoxyacetophenone → 3-(Dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Methoxyacetophenone | HCID 7476 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 3-(Dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one | HCID 722402 | — |
Reaction Steps
A mixture of 25 g. of p-methoxyacetophenone and 25 ml. of dimethylformamide dimethylacetal is refluxed for 9 hours. Evaporation gives an oil which crystallized on the addition of hexane. Recrystallization from methylene chloride and hexane gives the desired compound, m.p. 92°-95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04209621 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-76fb4e6b26464811b9cbda1ab5e7fe4f |
| Source note | uspto-grants-1980_06 |