3-Dimethylamino-3'-methoxyacrylophenone → HCID 20333371, compound

HRID 1707064Notes

Reaction equation

HRID 1707064 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.CN(C)[CH:9]=[CH:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=1)=O>C(O)(=O)C>[CH3:20][O:19][C:15]1[CH:14]=[C:13]([C:11]2[N:3]3[N:4]=[CH:5][N:6]=[C:2]3[N:1]=[CH:9][CH:10]=2)[CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 425737963-Dimethylamino-3'-methoxyacrylophenoneHCID 178418311HCID 178418311, compound

Product 1

HCID 20333371HCID 20333371, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 2.54 g. of 3-amino-1,2,4-triazole and 6.15 g. of 3-dimethylamino-3'-methoxyacrylophenone in 25 ml. of glacial acetic acid is refluxed for 6 hours. The resulting mixture is worked up as described in Example 54 to give the product of the Example, m.p. 163°-165° C.

Workup

  1. additionA mixture of 2.54 g
  2. customto give the product of the Example, m.p. 163°-165° C.

Sources & evidence

ORD record
ord-112940237066483886b34da20e889afe
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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