HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(Methylthio)-4-phenylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178527861 | HCID 178527861 | — |
| Product | 2-(Methylthio)-4-phenylpyrimidine | HCID 817578 | — |
Reaction Steps
A solution of 3.5 g. of 2-mercapto-4-phenylpyrimidine in 50 ml. of 1 N sodium hydroxide is cooled to near 0° C. and 2.94 g. of methyl iodide is added. After stirring at room temperature for 2 hours, the product is recovered by filtration. Recrystallization from methylene chloride-hexane affords the desired compound, m.p. 87°-89° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04209621 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-65280f7792e64c299729531a8f1eb82a |
| Source note | uspto-grants-1980_06 |