Hydrazine → 2-Hydrazinyl-4-phenylpyrimidine

HRID 1707071Notes

Reaction equation

HRID 1707071 reaction equation
CS([C:5]1[N:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[NH2:17][NH2:18]>C(O)C>[NH:17]([C:5]1[N:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=[CH:7][N:6]=1)[NH2:18]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 27674892-(methylsulfonyl)-4-phenylpyrimidine

Product 1

HCID 203333472-Hydrazinyl-4-phenylpyrimidine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 1.0 g. of 2-methylsulfonyl-4-phenylpyrimidine in 25 ml. of absolute ethanol is treated with 0.34 g. of 95% hydrazine. The reaction mixture is refluxed for 6 hours and then cooled and the desired product is obtained by filtration, m.p. 116°-118° C.

Workup

  1. temperatureThe reaction mixture is refluxed for 6 hours
  2. temperaturecooled

Sources & evidence

ORD record
ord-4967e964bed14f09b05d705cd6557581
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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