Hydrazine → HCID 20333332, compound

HRID 1707072Notes

Reaction equation

HRID 1707072 reaction equation
CS([C:5]1[N:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:20])([F:19])[F:18])[CH:12]=2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[NH2:21][NH2:22]>C(O)C>[NH:21]([C:5]1[N:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:20])([F:19])[F:18])[CH:12]=2)[CH:8]=[CH:7][N:6]=1)[NH2:22]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 20333322HCID 20333322, compound

Product 1

HCID 20333332HCID 20333332, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 6.0 g. of 2-methylsulfonyl-4-(m-trifluoromethylphenyl)pyrimidine in 75 ml. of absolute ethanol is treated with 1.9 g. of 95% hydrazine and is refluxed for 8 hours. Isolation as in the previous example gives the desired compound, m.p. 103°-106° C.; resolidifies and melts at 120°-122° C.

Sources & evidence

ORD record
ord-cc22e2cf01104d9db4c6406aca69b651
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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