Triethyl orthoacetate → HCID 20333337, compound

HRID 1707076Notes

Reaction equation

HRID 1707076 reaction equation
[NH:1]([C:3]1[N:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=2)[CH:6]=[CH:5][N:4]=1)[NH2:2].[C:19](OCC)(OCC)(OCC)[CH3:20]>>[CH3:19][C:20]1[N:4]2[CH:5]=[CH:6][C:7]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=3)=[N:8][C:3]2=[N:1][N:2]=1

Participants

3

Reactant 2

HCID 66221Triethyl orthoacetateHCID 20333332HCID 20333332, compound

Product 1

HCID 20333337HCID 20333337, compound

Procedure

A mixture of 1.0 g. of 2-hydrazino-4-(m-trifluoromethylphenyl)pyrimidine and 25 ml. of triethyl orthoacetate is refluxed for 12 hours. On cooling the desired compound is isolated by filtration, m.p. 232°-234° C.

Workup

  1. additionA mixture of 1.0 g

Sources & evidence

ORD record
ord-a11a47c99d5c493995d1e9f60ae0c0ce
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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