反应详情

A mixture of 21.1 g. of 2-chloro-5-(4-chlorophenyl)-pyridine and 19.5 g. of 95% hydrazine in 200 ml. of pyridine is heated at reflux temperature for 48 hours. The reaction mixture is cooled, poured into an ice-water mixture and filtered. The solid is collected, washed with water and air dried to yield 17.0 g. of the product of the Example as a tan solid.

1. additionA mixture of 21.1 g
2. temperatureat reflux temperature for 48 hours
3. temperatureThe reaction mixture is cooled
4. filtrationfiltered
5. customThe solid is collected
6. washwashed with water and air
7. customdried
8. customto yield 17.0 g