HRID1707144

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7918

Acetic anhydride

C4H6O3

HCID89715

1,3-Benzenediamine, N,N,N',N'-tetramethyl-

C10H16N2

结构：CN(C)c1ccc(C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)O)c(N(C)C)c1

HCID23343373

未命名化合物

PRODUCTS

生成物

结构：CN(C)c1ccc(C2(c3ccc(N(C)C)cc3N(C)C)OC(=O)c3c(Cl)c(Cl)c(Cl)c(Cl)c32)c(N(C)C)c1

HCID23343360

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8058

n-Hexane

C6H14

PROCEDURE

实验过程

A mixture of most of the 2-(2,4-bis(dimethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid from part A of this example, N,N,N',N'-tetramethyl-m-phenylenediamine (0.82 g. plus 0.4 g.) and acetic anhydride was heated under reflux. Concentration of a toluene extract of the resulting product gave a tar, which was slurried in hexane, affording 3,3-bis(2,4-bis(dimethylamino)phenyl)-4,5,6,7-tetrachlorophthalide (I: X=Y2 =Y4 =(CH3)2N, Z4 =Z5 =Z6 =Z7 =Cl) (m.p. 195°-197° C.).

WORKUP

后处理

temperaturewas heated
temperatureunder reflux
extractionConcentration of a toluene extract of the resulting product
customgave a tar, which

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-256181fcac96463fa111d4d645650b81
来源数据集: uspto-grants-1980_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04209618
来源说明: uspto-grants-1980_06

反应 SMILES

[CH3:1][N:2]([CH3:27])[C:3]1[CH:23]=[C:22]([N:24]([CH3:26])[CH3:25])[CH:21]=[CH:20][C:4]=1[C:5]([C:7]1[C:15]([Cl:16])=[C:14]([Cl:17])[C:13]([Cl:18])=[C:12]([Cl:19])[C:8]=1[C:9](O)=[O:10])=[O:6].[CH3:28][N:29]([CH3:39])[C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([N:36]([CH3:38])[CH3:37])[CH:31]=1.C(OC(=O)C)(=O)C>CCCCCC>[CH3:37][N:36]([CH3:38])[C:32]1[CH:31]=[C:30]([N:29]([CH3:39])[CH3:28])[CH:35]=[CH:34][C:33]=1[C:5]1([C:4]2[CH:20]=[CH:21][C:22]([N:24]([CH3:26])[CH3:25])=[CH:23][C:3]=2[N:2]([CH3:27])[CH3:1])[C:7]2[C:8](=[C:12]([Cl:19])[C:13]([Cl:18])=[C:14]([Cl:17])[C:15]=2[Cl:16])[C:9](=[O:10])[O:6]1