Ethanol → Trifluoromethyl toluidine

Participants

Reaction Conditions

Reaction Steps

Dissolve 2 g. of 3-amino-4-chloro-2-methylthiomethylbenzotrifluoride in 50 ml. of 90% ethanol which is 1 N in potassium hydroxide. Add 2 teaspoonfuls of Raney nickel (W-2). Stir at 70° C. for 3 hours, cool and filter. Add 50 ml. of water and extract three times with hexane. Dry and evaporate the combined organic extracts to yield the title compound.

Provenance & Evidence