Phosphorus pentachloride → HCID 54434434, compound

HRID 1707174Notes

Reaction equation

HRID 1707174 reaction equation
[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8](O)=[O:9])=[O:4].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C(Cl)Cl>[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8]([Cl:18])=[O:9])=[O:4]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 53711305HCID 53711305, compound

Product 1

HCID 54434434HCID 54434434, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To an ice-cold stirred suspension of 2-dichloroacetoxyimino-2-(fur-2-yl)acetic acid (1.5 g) in dry methylene chloride (70 mls) was added dropwise a freshly prepared solution of phosphorus pentachloride (1.0 equiv.) in methylene chloride. When solution was complete the solvent was evaporated at low temperature and the residual oil azeotroped with benzene to give 2-dichloroacetoxyimino-2(fur-2-yl)acetyl chloride (syn-isomer) as a pale yellow oil which was used directly.

Workup

  1. customwas evaporated at low temperature
  2. customthe residual oil azeotroped with benzene

Sources & evidence

ORD record
ord-1e5e09ee75d8448c9f8677c5b88f2005
Source dataset
uspto-grants-1980_06
Patent number
US04209616

Reaction notes

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