Benzyl piperazine-1-carboxylate → HCID 178525156, compound

HRID 1707251Notes

Reaction equation

HRID 1707251 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]3[CH2:15][CH2:14][C:13](=O)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1.[C:17]([N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1)([O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:18]>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C@H:10]3[CH2:15][CH2:14][C@H:13]([N:30]4[CH2:29][CH2:28][N:27]([C:17]([O:19][CH2:20][C:21]5[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=5)=[O:18])[CH2:32][CH2:31]4)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 643495Benzyl piperazine-1-carboxylateHCID 10932904AGN-PC-0ND25R

Product 1

HCID 178525156HCID 178525156, compoundYield 31%

Procedure

4-(1,3-Benzodioxol-5-yl)cyclohexanone and carbobenzyloxy piperazine were reacted as described in example 9 to give the product (31%, mp: 107°-108° C.). Calc'd for C25H30N2O4 : C, 71.07%; H, 7.16%; N, 6.64%. Found: C, 70.95%; H, 7.16%; N, 6.36%.

Sources & evidence

ORD record
ord-bd6fedc30fdb45eaa00861ce915769d1
Source dataset
uspto-grants-1994_10
Patent number
US05352678

Reaction notes

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