反应详情

42 g (0.11 mol) 1-bromo-7-(3-nitrophenyl-methylene)-6,8-nonanedione and 22 g (0.22 mmol) 2-amino-2-penten-4-one are boiled under reflux in 270 ml methanol for 20 h. The mixture is concentrated and the residue is chromatographed over silica gel with toluene/acetone=95/5. The title compound is obtained as a yellow oil. Yield: 22 g (44%).

1. concentrationThe mixture is concentrated
2. customthe residue is chromatographed over silica gel with toluene/acetone=95/5