HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 9819982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 67797294 | HCID 67797294 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | HCID 9819982 | HCID 9819982 | 95.6% |
Reaction Steps
A solution of 100 mg of 3-[2-[6-(4-methoxyphenyl)-(5E)5-hexenyloxy]-phenyl]-propionic acid methyl ester in 2 ml of methanol and 2 ml of in potassium hydroxide solution is stirred for 2 1/2 hours at room temperature. The reaction mixture is acidified to pH 1 with 2 n hydrochloric acid and shaken out with ethyl acetate, the organic phase is dried on sodium sulfate and concentrated by evaporation. 92 mg of the title compound is obtained as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05352701 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-9db43c8f69344f13a998112fc61db6a6 |
| Source note | uspto-grants-1994_10 |