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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1707358Generated: October 27, 2026

7-demethylmitomycin A → Mitomycin A

https://huagongshe.com/reaction/1707358

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-demethylmitomycin AHCID 11727393—
ReactantHCID 178486252HCID 178486252—
ProductMitomycin AHCID 19972—

Reaction Steps

7-Hydroxy-9a-methoxymitosane was alkylated with 3-methyl-l-p-tolyltriazene to give mitomycin A or with diazodiphenylmethane to give 7-(diphenylmethyl)oxy-9a-methoxymitosane (hereinafter 7-ODPM mitomycin).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05352798
Source datasetuspto-grants-1994_10
ORD IDord-2973d6ff188048828205ea705e833ff5
Source noteuspto-grants-1994_10