Acetone → HCID 10014818, compound

Participants

Reaction Steps

A mixture of 29.8 g (0.27 mol) of 3-thiophenecarboxaldehyde, 7.7 g (0.13 mol) of acetone, 80 mL of ethanol, 40 mL of water, and 2 mL of 10% aqueous sodium hydroxide was stirred for 15 hours at ambient temperature. The solid that crystallized from the mixture was collected by filtration, and is dried to give 29.2 g (46% yield) of E,E-1,5-di-(3-thienyl)-1,4-pentadien-3-one as a yellow solid. 1H NMR, IR, and FDMS analyses were consistent with the expected structure. Elemental analysis: Calcd for C13H10OS2 : C,63.38; H,4.09. Found: C,63.10; H,4.12.

Provenance & Evidence