Triethylamine → HCID 10546047, compound

Participants

Reaction Steps

A solution of 1(2-hydroxyethyl)-5-bromoindole (6 gm, 0.025 mol), t-butyldimethylsilyl chloride (4.5 gm, 0.03 mol) and triethylamine (4.2 ml, 0.03 mol) in CH2Cl2 (60 ml) was stirred for 12 hours at room temperature. The reaction mixture was then washed twice with H2O, dried over Na2SO4, filtered and concentrated in vacuo to provide the title compound as a yellow oil. 1H NMR was consistent with the desired structure.

Provenance & Evidence