Sodium Iodide → HCID 11777990, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5-chloromethylthio-2-methyl-1,3,4-thiadiazole (730 mg: 4 mMol.) in acetone (6 ml) is added sodium iodide (1.2 g: 2.0 equivalents: 8 mMol.), and the mixture is stirred at 55° C. for 2 hours. The reaction mixture is diluted with water and extracted with ethyl acetate. The extract is washed with water, dried over sodium sulfate and concentrated to give 5-iodomethylthio-2-methyl-1,3,4-thiadiazole (1.05 g) as yellow oil.

Provenance & Evidence