1,4'-Bipiperidine → HCID 15224906, compound

HRID 1707622Notes

Reaction equation

HRID 1707622 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[N:20]1([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[N:20]1([CH:26]2[CH2:31][CH2:30][N:29]([C:11]([N:10]3[CH2:9][C:8]4[CH:14]=[CH:15][CH:16]=[CH:17][C:7]=4[O:6][C:5]4[CH:18]=[CH:19][C:2]([Cl:1])=[CH:3][C:4]3=4)=[O:12])[CH2:28][CH2:27]2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 786071,4'-BipiperidineHCID 149759838-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride

Product 1

HCID 15224906HCID 15224906, compoundYield 86.9%

Procedure

The title compound of Example 2 (0.6 g, 2.0 mmol) was combined with 1,4'-bipiperidine (0.38 g, 2.2 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic purification, 0.74 g of the title product was obtained as a white solid.

Workup

  1. custompurification

Sources & evidence

ORD record
ord-9ad4b5f427ad4f6082caf16363177945
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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