tert-Butyl piperazine-1-carboxylate → HCID 15289252, compound

HRID 1707634Notes

Reaction equation

HRID 1707634 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][C:9]([OH:11])=O)[CH:2]=1.[C:12]([O:16][C:17]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)=[O:18])([CH3:15])([CH3:14])[CH3:13]>>[O:11]=[C:9]([N:22]1[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:18])[CH2:24][CH2:23]1)[CH2:8][CH2:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 2596243-(Pyridin-3-yl)propanoic acid

Product 1

HCID 15289252HCID 15289252, compound

Procedure

A sample of 3-pyridinepropanoic acid (0.1 g, 0.7 mmol) was reacted with t-butyloxycarbonyl piperazine (0.19 g, 1.0 mmol) by the method of Example 26 to produce 95 mg of the white solid title compound after chromatography.

Sources & evidence

ORD record
ord-74c25e5e91a440cd96b2f513ec0eae6a
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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