2-Furancarbonyl chloride → HCID 2980350, compound

HRID 1707636Notes

Reaction equation

HRID 1707636 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[O:14]1[CH:18]=[CH:17][CH:16]=[C:15]1[C:19](Cl)=[O:20]>>[O:14]1[CH:18]=[CH:17][CH:16]=[C:15]1[C:19]([N:11]1[CH2:12][CH2:13][N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[CH2:9][CH2:10]1)=[O:20]

Participants

3

Reactant 2

HCID 682422-Furancarbonyl chlorideHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 2980350HCID 2980350, compound

Procedure

t-Butyloxycarbonyl piperazine (2.0 g, 10.7 mmol) was reacted with furancarbonyl chloride (1.40 g, 10.7 mmol) by the method of Example 4. Following chromatography, a 2.25 g sample of the title compound was obtained.

Sources & evidence

ORD record
ord-ab631961834f401187e297c47451c23f
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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