N,N-Dimethylpiperidin-4-amine → HCID 15289268, compound

HRID 1707642Notes

Reaction equation

HRID 1707642 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[CH3:20][N:21]([CH3:28])[CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11]([N:25]3[CH2:26][CH2:27][CH:22]([N:21]([CH3:28])[CH3:20])[CH2:23][CH2:24]3)=[O:12])[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 417391N,N-Dimethylpiperidin-4-amineHCID 149759838-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride

Product 1

HCID 15289268HCID 15289268, compoundYield 24.4%

Procedure

The title compound of Example 2 (1.0 g, 3.40 mmol) was reacted with N,N-dimethyl-4-piperidinamine (0.48 g, 3.74 mmol) by the method of Example 4. Following chromatographic separation, 0.32 g of the title product was obtained.

Workup

  1. customseparation

Sources & evidence

ORD record
ord-d13e82c1b74a43399754013b41e7bbce
Source dataset
uspto-grants-1994_10
Patent number
US05354747

Reaction notes

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