HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(4-Pyridinyl)ethyl]piperazine → 8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(4-Pyridinyl)ethyl]piperazine | HCID 558685 | — |
| Reactant | 8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride | HCID 14975983 | — |
| Product | 8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepine | HCID 15224926 | 291.3% |
Reaction Steps
The title compound of Example 2 (0.38 g, 1.3 mmol) was combined with the product of Example 88 (0.25 g, 1.3 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic separation, 1.7 g of the white solid title product was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05354747 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-525a2e45e5144ec48c3316b67909b848 |
| Source note | uspto-grants-1994_10 |