1,3-Bis(3-nitrophenoxy)-5-trifluoromethylbenzene → 1,3-Bis(3-aminophenoxy)-5-trifluoromethylbenzene

Participants

Reaction Conditions

Reaction Steps

To a reducing apparatus equipped with a thermometer, reflux condenser and stirrer, 55 g (0.131 mol) of 1,3-bis(3-nitrophenoxy)-5-trifluoromethylbenzene, 150 g of methyl cellosolve and 5 g of 5% Pd/c having a moisture content of 50% were charged and reacted in a hydrogen atmosphere at 70°~80° C. for 4 hours. After finishing the reaction, the catalyst was filtered off. The filtrate was heated to 90° C., mixed with 140 g of water and cooled to room temperature. The precipitated crystals were filtered and dried under reduced pressure to obtain 1,3-bis(3-aminophenoxy)-5-trifluoromethyl benzene as colorless solid. The product was 41 g (87% yield) and had a melting point of 98.0°~98.6° C.

Provenance & Evidence