2,3-Dimethyl-4-hydroxy-7-methoxyindole → 4-methoxy-2,3-dimethyl-1H-indol-7-ol

HRID 1707756Notes

Reaction equation

HRID 1707756 reaction equation
C([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:20][CH3:21])=[C:13]2[C:17]=1[NH:16][C:15]([CH3:18])=[C:14]2[CH3:19])C1C=CC=CC=1.CC1NC2C(C=1C)=C(O)C=CC=2OC>>[CH3:18][C:15]1[NH:16][C:17]2[C:13]([C:14]=1[CH3:19])=[C:12]([O:20][CH3:21])[CH:11]=[CH:10][C:9]=2[OH:8]

Participants

3

Reactant 2

HCID 184594912,3-Dimethyl-4-hydroxy-7-methoxyindoleHCID 189625287-Benzyloxy-2,3-dimethyl-4-methoxyindole

Product 1

HCID 212009824-methoxy-2,3-dimethyl-1H-indol-7-ol

Procedure

2,3-Dimethyl-7-hydroxy-4-methoxyindole is prepared from 7-benzyloxy-2,3-dimethyl-4-methoxyindole according to the operating method described for the preparation of 2,3-dimethyl-4-hydroxy-7-methoxyindole (Example 7c). It melts at 159° C.

Sources & evidence

ORD record
ord-aad72515bd3741e79776307c528c6d27
Source dataset
uspto-grants-1994_10
Patent number
US05354870

Reaction notes

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