Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Allyl chloroformate | HCID 18052 | — |
| Reactant | HCID 15661460 | HCID 15661460 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15661461 | HCID 15661461 | — |
Reaction Steps
1-Hydroxymethyl-3-methylcarbonyl-9-fluorenone (135 mg) was dissolved in THF (4 ml), cooled to 0° C. under N2. Pyridine (51 μl, 1.2 eq) was added followed by allyloxycarbonyl chloride (70 μl, 1.2 eq). The reaction mixture was allowed to stir overnight allowing it to come to room temperature. The reaction mixture was diluted with methylene chloride, washed with water, sat'd NaCl sol'n, dried and evaporated. The product was purified by preparative tlc (80 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05356889 |
|---|
| Source dataset | uspto-grants-1994_10 |
|---|
| ORD ID | ord-088838e9634e4e9d919a7cbba2bbcce8 |
|---|
| Source note | uspto-grants-1994_10 |
|---|
