Methylamine → 4-bromo-N-methylbenzene-1-sulfonamide

Participants

Reaction Steps

A solution of 4-bromobenzenesulphonyl chloride (2.0 g) in THF (5 ml) was treated in two portions with aqueous methylamine (40%; 6 ml). The resulting exothermic reaction-was allowed to subside and the solution was diluted with water (10 ml) and extracted with dichloromethane (2×50 ml). The dried extract was evaporated to give the title compound as a white solid (2.0 g).

Provenance & Evidence