2-Methylimidazole → HCID 43289189, compound

Participants

Reaction Steps

There were dissolved, in 20 ml of dry N,N-dimethylformamide, 1.797 g of 4-(3-chloropropoxy)benzonitrile, 985 mg of 2-methylimidazole and 1 765 g of a 90% potassium t-butoxide, then the resulting solution was stirred at room temperature for 4.5 hours, poured into ice water, the resulting precipitates were filtered off and washed with water. The precipitates were recrystallized from a mixed solution of ethanol and water to give 1.682 g (yield 69.7%) of 4-[3-(2-methylimidazol-1-yl) propoxy]benzonitrile.

Provenance & Evidence