HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1708148Generated: October 26, 2026
Diethyl (ethoxymethylene)malonate → 6-Propyl-3,5-diethoxycarbonyl-2-oxo-1,2-dihydropyridine
https://huagongshe.com/reaction/1708148
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | Ethyl 3-amino-hex-2-enoate | HCID 85320704 | — |
| Product | 6-Propyl-3,5-diethoxycarbonyl-2-oxo-1,2-dihydropyridine | HCID 23352083 | — |
Reaction Steps
62.8 g (0.4 mol) of ethyl 3-amino-hex-2-en-oate and 86.4 g (0.4 mol) of diethyl ethoxymethylenemalonate are stirred at 100° C. for 40 hours. The mixture is cooled to 20° C. and the solid is filtered off with suction and recrystallised from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05356911 |
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| Source dataset | uspto-grants-1994_10 |
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| ORD ID | ord-2b895592587a448b9707d878196e132c |
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| Source note | uspto-grants-1994_10 |
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