Ethanol, 2-amino-, 1-nitrate, nitrate (1:1) → HCID 57018110, compound

HRID 1708195Notes

Reaction equation

HRID 1708195 reaction equation
[O:1]=[C:2]1[NH:6][C@H:5]([C:7]([OH:9])=O)[C@@H:4]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[O:3]1.[N+]([O-])(O)=O.[N+:20]([O:23][CH2:24][CH2:25][NH2:26])([O-:22])=[O:21]>>[N+:20]([O:23][CH2:24][CH2:25][NH:26][C:7]([C@@H:5]1[C@@H:4]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[O:3][C:2](=[O:1])[NH:6]1)=[O:9])([O-:22])=[O:21]

Participants

3

Reactant 2

HCID 78397Ethanol, 2-amino-, 1-nitrate, nitrate (1:1)HCID 14442820HCID 14442820, compound

Product 1

HCID 57018110HCID 57018110, compoundYield 38.9%

Procedure

A procedure similar to that described in Example 19 was repeated, but using 130 mg of (4S,5R)-2-oxo-5-phenyloxazolidine-4-carboxylic acid and 127 mg of N-(2-nitrooxyethyl)amine nitrate, to obtain 72 mg of the title compound as colorless plates, melting at 122°-124° C.

Sources & evidence

ORD record
ord-0e2b2f18870c49358a9d636bba742597
Source dataset
uspto-grants-1994_10
Patent number
US05356918

Reaction notes

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