HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl p-aminosalicylate → HCID 18961218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl p-aminosalicylate | HCID 77787 | — |
| Reactant | 5-Methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxylic acid | HCID 13961648 | — |
| Product | HCID 18961218 | HCID 18961218 | 59.1% |
Reaction Steps
Following a procedure analogous to Example 12, 5-methoxy-3-(1-methylethoxy)benzo[b]thiophene-2-carboxylic acid (200 mg, 0.75 mmol) and methyl 4-aminosalicylate (117 mg, 0.70 mmol) [obtained by esterification of 4-aminosalicylic acid, sodium salt (Sigma) with iodomethane] provides 172 mg (59%) of product; mp 158.5°-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05356926 |
| Source dataset | uspto-grants-1994_10 |
| ORD ID | ord-03ab4ac33ba243e98054c2cc57251343 |
| Source note | uspto-grants-1994_10 |